Numbing® 5 % is a non-oily, translucent topical anesthetic gel containing lidocaine 5% in a microemulsion with skin permeation enhancers and soothing agents.
This is the maximum concentration allowed by FDA for an over-the-counter (non-prescription required) skin numbing agent.
TOPICAINE® is also available in 4% STRENGTH, containing lidocaine 4% in a similar vehicle.
WHAT IS IT FOR?
Numbing® 5% has lidocaine 5% in a gel with label indication: for anorectal pain. When applied to the perianal region, it quickly numbs the skin. Not to be used inside the rectum.
It is a TOPICAL ANESTHETIC specially formulated to penetrate intact skin, for the relief of pain. It is a skin numbing agent with lidocaine 5% as its active ingredient.
Numbing® 4% is a closely related product, which contains lidocaine 4%, and is indicated for the prevention and relief of pain caused by:
- minor skin irritations
- minor burns, including sunburn
- minor cuts
- insect bites
Physicians and esthetic professionals use this skin numbing gel for a number of medical and beauty treatments (these are off-label uses). Check with your physician or nurse practitioner to see if Numbing® 5% or 4% use is appropriate for your particular case and application.
HOW NUMB WILL MY SKIN GET?
"Numbing® demonstrated a very rapid onset with a long duration of cutaneous anesthesia in a prospective, randomized, double-blind, controlled study investigating the efficacy of EMLA®, LMX-5® and Numbing® using a 30-minute application time."
The effective skin numbing action of TOPICAINE® allows you to concentrate on getting results, not on enduring pain. You won't be cancelling your next appointment because of the dreadful pain.
Numbing®'s numbs the skin with rapid onset and proven efficacy.
Found it that Numbing® (with lidocaine 4% ) reduces pain better than LMX-5 (with lidocaine 5%) and prescription cream EMLA (which has a combination of 2.5% lidocaine and 2.5% prilocaine).
The explanation for this is that TOPICAINE® is formulated in a penetrating vehicle, with skin permeation enhancers that facilitate the delivery of lidocaine to where it needs to act.
HOW FAST IS THE SKIN NUMBING ACTION?
Excellent skin numbing results are obtained 30 minutes to 1 hour post application.
Please be a little patient - give the product time to work!
That way, you obtain the most benefit out of it.
Don't fall for other products that promise "instant numbing". Unless the skin is broken, is not going to happen.
That said, some areas of the body numb faster than others. For example, if you put some of the gel on your lips (the red part), you will feel numb - really numb - in less than ten minutes. That is because the skin there is very permeable. Try it yourself, once you get the product, and you will believe it!
However, most other areas of the body take more time, because the skin elsewhere is thicker, with many keratinized layers that act as a barrier.
TOPICAINE® is formulated to overcome this barrier, because it contains skin permeation enhancers. These are substances that temporarily and reversibly increase the permeability of the stratum corneum - the skin barrier.
In addition, the product needs some time to penetrate to where the pain receptors are located, deep into the dermis. In some areas, like the lips, the numbing action can be felt much faster because the nerve receptors are located very superficially. Most other locations of the body the receptors are located deeper, and it takes longer to reach them.